Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875866 | 0.80 | RAB9A (0.33) | MALT1EDNRBHPGDSMN1; SMN2 | |
| SCHEMBL6982527 | 0.78 | NPC1 (0.41) | ADRA1BMALT1ADRA1ASMN1; SMN2 | |
| SCHEMBL6983872 | 0.76 | MC4R (0.42) | ADRA1B | |
| SCHEMBL6983790 | 0.75 | KMT2A (0.39) | ADRA1BMALT1ADRA1AL3MBTL1HPGD | |
| SCHEMBL6985492 | 0.74 | POLB (0.38) | ADRA1BADRA1AL3MBTL1POLB | |
| SCHEMBL6985684 | 0.72 | ADRA1B (0.47) | ADRA1BADRA1AL3MBTL1 | |
| SCHEMBL6986641 | 0.72 | EPHX2 (0.38) | L3MBTL1 | |
| SCHEMBL4875878 | 0.71 | RAB9A (0.36) | MALT1HPGDSMN1; SMN2POLB | |
| SCHEMBL6985013 | 0.71 | KMT2A (0.39) | ADRA1BADRA1AL3MBTL1HPGDPOLB | |
| SCHEMBL6987065 | 0.71 | POLB (0.39) | ADRA1BADRA1AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |