Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986949 | 0.93 | SLC2A1 (0.48) | LPAR1LPAR5NR3C2AOC3SLC2A1 | |
| SCHEMBL6989313 | 0.90 | SMN1; SMN2 (0.47) | LPAR1LPAR5MRGPRX4KDM6BKDM5A | |
| SCHEMBL6990109 | 0.87 | LPAR1 (0.53) | LPAR1LPAR5MRGPRX4AKR1C3NR3C2 | |
| SCHEMBL6989317 | 0.83 | SMN1; SMN2 (0.47) | SLC2A1SLC2A4RAB9ASMN1; SMN2POLB | |
| SCHEMBL6993029 | 0.83 | ALDH1A1 (0.48) | MRGPRX4KDM6BKDM5AKDM4DKDM4C | |
| SCHEMBL6990355 | 0.81 | SLC2A1 (0.61) | LPAR1LPAR5SLC2A1SLC2A4SMN1; SMN2 | |
| SCHEMBL6990114 | 0.80 | LPAR1 (0.49) | LPAR1LPAR5NR3C2AOC3SLC2A1 | |
| SCHEMBL6985928 | 0.79 | KDM5B (0.49) | AKR1C3NR3C2KDM6BKDM5AKDM4D | |
| SCHEMBL6239722 | 0.79 | KDM5B (0.49) | LPAR1LPAR5KDM6BKDM5AKDM4D | |
| SCHEMBL6989792 | 0.78 | MEN1 (0.45) | LPAR1LPAR5KDM6BKDM5AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |