Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994882 | 0.99 | PTPN1 (0.31) | PNMTPTPN1 | |
| SCHEMBL6993141 | 0.91 | MEN1 (0.32) | PNMT | |
| SCHEMBL9041754 | 0.87 | PTPN1 (0.34) | MAOBPTPN1 | |
| SCHEMBL6982789 | 0.85 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL9041444 | 0.84 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL9038657 | 0.83 | — | — | |
| SCHEMBL6987269 | 0.80 | L3MBTL1 (0.38) | — | |
| SCHEMBL6986608 | 0.80 | L3MBTL1 (0.38) | — | |
| SCHEMBL9265702 | 0.79 | TBXAS1 (0.41) | — | |
| SCHEMBL9266055 | 0.79 | HTR1A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551527-B1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5397780-A | Antiserotonine, hypotensive, congestive heart failure | SUNTORY LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0551527-A1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |