SCHEMBL9265702

SCHEMBL9265702

CN1CCC(=O)c2ccn(CCCCn3ccnc3)c2C1=O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 4/20 0.41
PRKCI P41743 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6994882 0.80 PTPN1 (0.31)
SCHEMBL6982789 0.80 PTPN1 (0.35)
SCHEMBL9041444 0.79 PTPN1 (0.35)
SCHEMBL6992176 0.78 TBXAS1 (0.43) TBXAS1
SCHEMBL6991215 0.76 HTR1A (0.54)
SCHEMBL6998066 0.73 PTPN1 (0.33)
SCHEMBL9039006 0.71 SIGMAR1 (0.47)
SCHEMBL6984668 0.71 KDM4E (0.50)
SCHEMBL6987227 0.71 DRD2 (0.52)
SCHEMBL9039146 0.71 PKN2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397780-A Antiserotonine, hypotensive, congestive heart failure SUNTORY LIMITED (JP) 1995-03-14 US disclosed
EP-0551527-A1 PYRROLOAZEPINE DERIVATIVE SUNTORY LIMITED (JP) 1993-07-21 EP disclosed