Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989751 | 0.99 | PNMT (0.32) | PTPN1PNMT | |
| SCHEMBL6993141 | 0.92 | MEN1 (0.32) | PNMT | |
| SCHEMBL6982789 | 0.86 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL9041754 | 0.85 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL9041444 | 0.85 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL9038657 | 0.84 | — | — | |
| SCHEMBL9265702 | 0.80 | TBXAS1 (0.41) | — | |
| SCHEMBL6988025 | 0.79 | L3MBTL1 (0.39) | — | |
| SCHEMBL6987269 | 0.78 | L3MBTL1 (0.38) | — | |
| SCHEMBL6986608 | 0.78 | L3MBTL1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551527-B1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0441349-B1 | Pyrroloazepine derivatives | SUNTORY LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5397780-A | Antiserotonine, hypotensive, congestive heart failure | SUNTORY LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0551527-A1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |