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Sugi Predict / Compounds / SCHEMBL699048

SCHEMBL699048

SCHEMBL699048

CC(C)(C)OC(=O)NCCCCC(N)CN(CCN)CCN(CCN)CCN

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ GAA P10253 1/20 0.48
▸ TDP1 Q9NUW8 4/20 0.47
▸ MAOA P21397 1/20 0.45
▸ MAOB P27338 1/20 0.45
▸ CA1 P00915 11/20 0.40
▸ CA2 P00918 11/20 0.40
▸ CA12 O43570 6/20 0.40
▸ CA9 Q16790 6/20 0.40
▸ ATM Q13315 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ MAPT P10636 1/20 0.34
▸ GNAI3 P08754 1/20 0.34
▸ GNAO1 P09471 1/20 0.34
▸ GNAI1 P63096 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17175570 0.94 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
SCHEMBL11990363 0.93 MEN1 (0.44) MEN1KMT2AGAATDP1MAOA
SCHEMBL17972765 0.93 TDP1 (0.51) MEN1KMT2AGAATDP1MAOA
SCHEMBL12432862 0.92 MAOA (0.45) MEN1KMT2AGAATDP1MAOA
SCHEMBL19050938 0.90 TDP1 (0.55) MEN1KMT2AGAATDP1MAOA
SCHEMBL17175287 0.88 MEN1 (0.47) MEN1KMT2AGAATDP1MAOA
SCHEMBL19416426 0.87 MAOA (0.45) MEN1KMT2AGAATDP1MAOA
SCHEMBL17972782 0.87 MEN1 (0.41) MEN1KMT2AGAATDP1MAOA
SCHEMBL15739536 0.87 MEN1 (0.41) MEN1KMT2AGAATDP1MAOA
SCHEMBL15716848 0.85 MEN1 (0.41) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691997-B2 Macrocycles LUMIPHORE, INC. (US) 2023-07-04 — — US disclosed
US-11691997-B2 Macrocycles LUMIPHORE, INC. (US) 2023-07-04 — — US disclosed
US-11453652-B2 Di-macrocycles LUMIPHORE, INC. (US) 2022-09-27 — — US disclosed
EP-3129350-B1 MACROCYCLES LUMIPHORE INC (US) 2021-10-27 — — EP disclosed
EP-2051968-B1 LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES UNIV CALIFORNIA (US) 2020-04-29 — — EP disclosed
EP-2920157-B1 DI-MACROCYCLES LUMIPHORE INC (US) 2019-09-11 — — EP disclosed
EP-2920157-B1 DI-MACROCYCLES LUMIPHORE INC (US) 2019-09-11 — — EP disclosed
EP-2511266-B1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES UNIV CALIFORNIA (US) 2019-09-04 — — EP disclosed
US-10273256-B2 Macrocycles LUMIPHORE, INC. (US) 2019-04-30 — — US disclosed
EP-3263562-A1 RADIOPHARMACEUTICAL COMPLEXES Lumiphore, Inc. (US) 2018-01-03 — — EP disclosed
US-20100167289-A1 MULTI-COLOR TIME RESOLVED FLUOROPHORES BASED ON MACROCYCLIC LANTHANIDE COMPLEXES LUMIPHORE, INC. 2010-07-01 — — US disclosed
US-20100167289-A1 MULTI-COLOR TIME RESOLVED FLUOROPHORES BASED ON MACROCYCLIC LANTHANIDE COMPLEXES LUMIPHORE, INC. 2010-07-01 — — US disclosed
US-20100015725-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-01-21 — — US disclosed
EP-2044090-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-08 — — EP disclosed
US-20080213780-A1 Hydroxy-isophthalamide moieties bind antigens/proteins; high stability as well and quantum yields of luminescence in aqueous media without the need for secondary activating agents LUMIPHORE, INC. (US) 2008-09-04 — — US disclosed
US-20080213780-A1 Hydroxy-isophthalamide moieties bind antigens/proteins; high stability as well and quantum yields of luminescence in aqueous media without the need for secondary activating agents LUMIPHORE, INC. (US) 2008-09-04 — — US disclosed
US-20080213917-A1 LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-04 — — US disclosed
US-20080213917-A1 LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-04 — — US disclosed
WO-2008092120-A1 MULTI-COLOR TIME RESOLVED FLUOROPHORES BASED ON MACROCYCLIC LANTHANIDE COMPLEXES LUMIPHORE, INC. (US) 2008-07-31 — — WO disclosed
WO-2008008797-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080213917-A1 LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES SSB, HACD3, CLTA MEN1 1772/4885KMT2A 3655/4885GAA 1305/4885
US-11691997-B2 Macrocycles HCCS, ABCB7, AURKAIP1 MEN1 377/4885KMT2A 4535/4885GAA 2085/4885
US-11453652-B2 Di-macrocycles DLD, NDC1, MCL1 MEN1 220/4885KMT2A 4469/4885GAA 2024/4885
US-10273256-B2 Macrocycles HCCS, ABCB7, AURKAIP1 MEN1 377/4885KMT2A 4535/4885GAA 2085/4885
US-20100167289-A1 MULTI-COLOR TIME RESOLVED FLUOROPHORES BASED ON MACROCYCLIC LANTHANIDE COMPLEXES HACD3, CLTA, HDHD5 MEN1 2484/4885KMT2A 1464/4885GAA 1097/4885
US-20080213780-A1 Hydroxy-isophthalamide moieties bind antigens/proteins; high stability as well and quantum yields of luminescence in aqueous media without the need for secondary activating agents LY96, SSB, UACA MEN1 2593/4885KMT2A 2534/4885GAA 1089/4885
US-20100015725-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES PLPBP, HPD, LASP1 MEN1 1167/4885KMT2A 3670/4885GAA 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.