Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP10 | P09238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995857 | 0.73 | MMP1 (0.46) | S1PR5FFAR1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2409029 | 0.71 | MMP1 (0.50) | ALDH1A1SMN1; SMN2GAAKDM4EMMP1 | |
| SCHEMBL8425464 | 0.70 | S1PR5 (0.44) | S1PR5FFAR1ALDH1A1PTGDR2HPGD | |
| SCHEMBL7001941 | 0.68 | MMP1 (0.56) | ALDH1A1KDM4EHPGDHTTNPSR1 | |
| SCHEMBL6998853 | 0.68 | MMP1 (0.56) | ALDH1A1KDM4EHPGDHTTNPSR1 | |
| SCHEMBL7308927 | 0.66 | MMP1 (0.50) | ALDH1A1SMN1; SMN2GAAKDM4EMMP1 | |
| SCHEMBL7304591 | 0.66 | MMP1 (0.64) | MMP1MMP13ABCB11MMP2MMP3 | |
| SCHEMBL8425539 | 0.65 | FKBP1A (0.42) | S1PR5ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7302178 | 0.65 | MMP1 (0.46) | ALDH1A1SMN1; SMN2MMP1MMP13MAPT | |
| SCHEMBL11540586 | 0.64 | ALDH1A1 (0.83) | FFAR1ALDH1A1SMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070069-B1 | BICYCLIC HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-07-16 | — | — | EP | disclosed |