Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608750 | 0.84 | PPARG (0.38) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL2550357 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL30222010 | 0.79 | MAPT (0.42) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL2023656 | 0.79 | MAPT (0.42) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL1315082 | 0.78 | MAPK1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL30480018 | 0.78 | MAPK1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL10714313 | 0.78 | ALDH1A1 (0.39) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL2550779 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL202312 | 0.76 | DHFR (0.40) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL3656667 | 0.76 | DHFR (0.40) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4808401-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| US-7767864-B2 | Process for the hydroformylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-08-03 | — | — | US | claimed |
| EP-1527038-B1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INT UK LTD (GB) | 2010-03-17 | — | — | EP | claimed |
| US-20080051475-A1 | Process for the Hydroformylation of Ethylenically Unsaturated Compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2008-02-28 | — | — | US | claimed |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2006-06-08 | — | — | US | claimed |
| JP-2005535695-A | — | — | 2005-11-24 | — | — | JP | claimed |
| EP-1527038-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | Lucite International UK Limited (GB) | 2005-05-04 | — | — | EP | claimed |
| CN-1140532-C | Process for preparation of bisphosphines | 卢西特国际英国有限公司 | 2004-03-03 | — | — | CN | claimed |
| WO-2004014834-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| EP-1003754-B1 | METHOD OF MANUFACTURING PHOSPHINE COMPOUND | LUCITE INT UK LTD (GB) | 2004-02-11 | — | — | EP | claimed |
| EP-1064288-B1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | LUCITE INT UK LTD (GB) | 2003-05-02 | — | — | EP | claimed |
| CN-1293675-A | Process for preparation of bisphosphines | INIOS ACRYLIC ACID BRITISH PLC (GB) | 2001-05-02 | — | — | CN | claimed |
| EP-1064288-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | Ineos Acrylics UK Limited (GB) | 2001-01-03 | — | — | EP | claimed |
| WO-1999047528-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | INEOS ACRYLICS UK LIMITED (GB) | 1999-09-23 | — | — | WO | claimed |
| EP-1688424-B1 | PHOSPHONIUM BORATE COMPOUND AND METHOD OF USING THE SAME | HOKKO CHEM IND CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-2552928-B1 | A PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST. | CHROMAFORA AB (SE) | 2015-04-15 | — | — | EP | disclosed |
| US-8735629-B2 | Process for the reduction of a tertiary phosphine oxide to the corresponding tertiary phosphine in the presence of a catalyst and use of a tertiary phosphine for reducing a tertiary phosphine oxide in the presence of a catalyst | CHROMAFORA AB (SE) | 2014-05-27 | — | — | US | disclosed |
| WO-1999009040-A1 | METHOD OF MANUFACTURING PHOSPHINE COMPOUND | INEOS ACRYLICS UK LIMITED (GB) | 1999-02-25 | — | — | WO | disclosed |
| EP-0799180-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENE AND CATALYST SYSTEM FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019434-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENE AND CATALYST SYSTEM FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051475-A1 | Process for the Hydroformylation of Ethylenically Unsaturated Compounds | ETV6, DHPS, ELOVL6 | ALDH1A1 1441/4885CYP2A6 110/4885HSD17B10 1005/4885 |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | CYC1, CYCS, COX5A | ALDH1A1 1472/4885CYP2A6 253/4885HSD17B10 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.