Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004554 | 0.90 | BAZ2B (0.39) | BAZ2BBAZ2ACA12CA1CA2 | |
| SCHEMBL7003687 | 0.84 | ESR1 (0.37) | BAZ2BBAZ2AGPR35CYP1A2CYP2C19 | |
| SCHEMBL7008752 | 0.83 | BAZ2B (0.48) | BAZ2BBAZ2ACA12CA1CA2 | |
| SCHEMBL7556806 | 0.82 | BAZ2B (0.38) | BAZ2BBAZ2ACA12CA1CA2 | |
| SCHEMBL7005984 | 0.82 | BAZ2B (0.40) | BAZ2BBAZ2ACA12CA1CA2 | |
| SCHEMBL7002598 | 0.80 | CRHBP (0.53) | PKMMAPTALDH1A1GAAKDM4E | |
| SCHEMBL7006414 | 0.74 | ESR1 (0.39) | BAZ2BBAZ2AMAPTGPR35ALDH1A1 | |
| SCHEMBL7000138 | 0.73 | ESR1 (0.36) | BAZ2BBAZ2AGPR35ESR1L3MBTL1 | |
| SCHEMBL7555501 | 0.72 | GPR35 (0.36) | BAZ2BBAZ2AGPR35ALDH1A1POLB | |
| SCHEMBL7008527 | 0.70 | BAZ2B (0.45) | BAZ2BBAZ2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |