Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556806 | 0.82 | BAZ2B (0.38) | BAZ2BBAZ2AALDH1A1POLBADRA1D | |
| SCHEMBL7006414 | 0.80 | ESR1 (0.39) | GPR35BAZ2BBAZ2AALDH1A1POLB | |
| SCHEMBL7000138 | 0.79 | ESR1 (0.36) | GPR35BAZ2BBAZ2A | |
| SCHEMBL7006368 | 0.78 | PTGS1 (0.32) | ADRA1DPTGS1 | |
| SCHEMBL7003687 | 0.78 | ESR1 (0.37) | GPR35BAZ2BBAZ2APOLB | |
| SCHEMBL7004554 | 0.75 | BAZ2B (0.39) | GPR35BAZ2BBAZ2AALDH1A1POLB | |
| SCHEMBL7010259 | 0.73 | ESR1 (0.39) | GPR35BAZ2BBAZ2AALDH1A1NOTUM | |
| SCHEMBL7004657 | 0.72 | BAZ2B (0.39) | GPR35BAZ2BBAZ2AALDH1A1POLB | |
| SCHEMBL7004077 | 0.72 | SLC6A5 (0.38) | ALDH1A1 | |
| SCHEMBL7006924 | 0.72 | CRHBP (0.44) | ALDH1A1CRHBPCRHR2F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |