SCHEMBL266229

SCHEMBL266229

CCCCC[CH]S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
PPARA Q07869 2/20 0.42
EPHX2 P34913 1/20 0.41
TP53 P04637 1/20 0.40
EP300 Q09472 1/20 0.40
FAAH O00519 3/20 0.39
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954181 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL27809538 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL27588305 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL699652 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL27526927 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL700497 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL9012336 0.98 TSHR (0.48) TSHRPPARAEPHX2EP300FAAH
SCHEMBL101407 0.92
SCHEMBL25090 0.81
SCHEMBL3034952 0.77 TSHR (0.46) TSHRPPARATP53FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732512-B1 INHALANT FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN AND CORTICOSTEROID CYDEX PHARMACEUTICALS INC (US) 2017-03-22 EP claimed
US-20240156766-A1 INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS, INC. (US) 2024-05-16 US disclosed
US-20240139137-A1 Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same CYDEX PHARMACEUTICALS, INC. 2024-05-02 US disclosed
US-20240009151-A1 FORMULATIONS OF AZOBENZENE PHOTOREACTIVE COMPOUNDS BAYON THERAPEUTICS, INC. 2024-01-11 US disclosed
EP-4274561-A1 PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES Quadriga Biosciences, Inc. (US) 2023-11-15 EP disclosed
US-20230357451-A1 ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2023-11-09 US disclosed
US-20230348631-A1 PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES QUADRIGA BIOSCIENCES, INC. 2023-11-02 US disclosed
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same CYDEX PHARMACEUTICALS, INC. (US) 2023-10-24 US disclosed
CN-116847855-A Pharmaceutical composition of chemotherapeutic agents based on beta-substituted beta-amino acid derivatives 夸德里加生物科学公司 2023-10-03 CN disclosed
US-20230255919-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2023-08-17 US disclosed
US-6143905-A REACTING 1,7-DIBROMOPERYLENE-3,4,9,10-TETRACARBOXYLIC DIANHYDRIDE OR TETRACARBOXYLIC ACID IN PRESENCE OF APROTIC SOLVENT WITH A PRIMARY AMINE TO FORM DIIMIDE, REACTING DIIMIDE WITH AROMATIC ALOCHOL OR THIOL, AND HYDROLYZING BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
EP-0869959-B1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AG (DE) 2000-05-17 EP disclosed
US-6063181-A 1,7-disubstituted perylene-3,4,9, 10-tetracarboxylic acids, their dianhydrides and diimides of said acids BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
EP-0873342-A1 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
EP-0869959-A1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AKTIENGESELLSCHAFT (DE) 1998-10-14 EP disclosed
WO-1997022607-A1 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES BASF AKTIENGESELLSCHAFT (DE) 1997-06-26 WO disclosed
WO-1997022608-A1 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS BASF AKTIENGESELLSCHAFT (DE) 1997-06-26 WO disclosed
EP-0089834-B1 LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1987-09-09 EP disclosed
US-4482629-A 1-NAPHTHOL COUPLER TO REACT WEITH OXIDIZED COLOR-FORMING DEVELOPER; ALKALISOLUBLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-11-13 US disclosed
EP-0089834-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348631-A1 PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES BCAT1, BCAT2, DDC TSHR 4801/4885PPARA 1397/4885EPHX2 3389/4885
US-11795241-B2 Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same AGPS, DDOST, ALG1 TSHR 4344/4885PPARA 2741/4885EPHX2 481/4885
US-20240156766-A1 INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME MCL1, MYADM, IL2 TSHR 3288/4885PPARA 3954/4885EPHX2 2684/4885
US-20230255919-A1 COMPOSITION CONTAINING CYCLODEXTRIN AND BUSULFAN SBDS, HBG1, CD99 TSHR 4091/4885PPARA 2188/4885EPHX2 3341/4885
US-20240139137-A1 Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same GYS2, NOTUM, PYGL TSHR 4211/4885PPARA 3759/4885EPHX2 3184/4885
US-20240009151-A1 FORMULATIONS OF AZOBENZENE PHOTOREACTIVE COMPOUNDS CRY1, PDE6C, PDE6D TSHR 3029/4885PPARA 1101/4885EPHX2 2396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.