Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064750 | 0.80 | ALDH1A1 (0.36) | ALDH1A1POLBHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL2812495 | 0.77 | ALDH1A1 (0.39) | ALDH1A1POLBHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL3510746 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBHSD11B1KDM4EHTT | |
| SCHEMBL135098 | 0.74 | LMNA (0.33) | ALDH1A1HSD11B1HSD11B2LMNAHTT | |
| SCHEMBL26217994 | 0.72 | ALDH1A1 (0.38) | ALDH1A1POLBHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL30477996 | 0.72 | HSD11B1 (0.46) | ALDH1A1POLBHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL6491717 | 0.72 | ALDH1A1 (0.38) | ALDH1A1POLBHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL8097478 | 0.72 | HSD11B1 (0.48) | ALDH1A1POLBHSD11B1KDM4EHTT | |
| SCHEMBL703301 | 0.72 | EPHX2 (0.38) | ALDH1A1POLBHSD11B1HSD11B2 | |
| SCHEMBL26881005 | 0.69 | MEN1 (0.33) | HSD11B1HSD11B2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802348-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2014-08-12 | — | — | US | disclosed |
| US-8377627-B2 | Compound and radiation-sensitive composition | JSR CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-1961739-B1 | NOVEL COMPOUND, POLYMER, AND RESIN COMPOSITION | JSR CORP (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-8273837-B2 | Compound, polymer, and resin composition | JSR CORPORATION (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120164586-A1 | PATERN FORMING METHOD | JSR CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| US-8182977-B2 | Polymer and positive-tone radiation-sensitive resin composition | JSR CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8173351-B2 | Compound and radiation-sensitive composition | JSR CORPORATION (JP) | 2012-05-08 | — | — | US | disclosed |
| US-8124314-B2 | Radiation-sensitive composition | JSR CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8084188-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20110117489-A1 | COMPOUND AND RADIATION-SENSITIVE COMPOSITION | JSR CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20100221664-A1 | RADIATION-SENSITIVE COMPOSITION | JSR CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20100203452-A1 | RADIATION-SENSITIVE COMPOSITION | JSR CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| US-20100203447-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| US-20100068647-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20090318652-A1 | NOVEL COMPOUND, POLYMER, AND RESIN COMPOSITION | JSR CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090305161-A1 | LIQUID IMMERSION LITHOGRAPHY | JSR CORPORATION (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090274977-A1 | COMPOUND AND RADIATION-SENSITIVE COMPOSITION | JSR CORPORATION (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-2100870-A1 | COMPOUND AND RADIATION-SENSITIVE COMPOSITION | JSR Corporation (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-1961739-A1 | NOVEL COMPOUND, POLYMER, AND RESIN COMPOSITION | JSR Corporation (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-1953595-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2008-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318652-A1 | NOVEL COMPOUND, POLYMER, AND RESIN COMPOSITION | ERCC4, RAD51, RTF1 | ALDH1A1 4177/4885POLB 436/4885HSD11B1 3942/4885 |
| US-20110117489-A1 | COMPOUND AND RADIATION-SENSITIVE COMPOSITION | ERCC2, RAD51, ATM | ALDH1A1 1835/4885POLB 280/4885HSD11B1 1031/4885 |
| US-20090274977-A1 | COMPOUND AND RADIATION-SENSITIVE COMPOSITION | RAD51, SLC11A2, XRCC6 | ALDH1A1 2392/4885POLB 723/4885HSD11B1 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.