Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | DCK | P27707 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900467 | 0.89 | DCK (0.43) | ALDH1A1LMNADCKPOLB | |
| SCHEMBL12932953 | 0.88 | HTR6 (0.43) | LMNADCKHTR6MMP2TSHR | |
| SCHEMBL1271033 | 0.86 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALDH1A1DCK | |
| SCHEMBL1270873 | 0.85 | DCK (0.49) | MEN1KMT2AALDH1A1LMNADCK | |
| SCHEMBL12900482 | 0.85 | HTR6 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL12900461 | 0.83 | NOD1 (0.45) | ALDH1A1DCKNOD1HTR6 | |
| SCHEMBL7014244 | 0.83 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7010844 | 0.83 | CA1 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12900473 | 0.82 | DCK (0.44) | MEN1KMT2AMAPTLMNACA1 | |
| SCHEMBL12900471 | 0.80 | DCK (0.38) | KMT2ACA1CA2DCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426033-B1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL CO (JP) | 2020-09-16 | — | — | EP | claimed |
| EP-3426033-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company Limited (JP) | 2019-01-16 | — | — | EP | claimed |
| EP-3426035-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company Limited (JP) | 2019-01-16 | — | — | EP | claimed |
| EP-3426034-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | Sumitomo Chemical Company Limited (JP) | 2019-01-16 | — | — | EP | claimed |
| WO-2017155091-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-14 | — | — | WO | claimed |
| WO-2017155089-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-14 | — | — | WO | claimed |
| WO-2017155090-A1 | SYNERGISTIC FUNGICIDAL COMPOSITION FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-14 | — | — | WO | claimed |
| US-20240351990-A1 | PROCESS FOR PREPARING 5-FLUORO-4-IMINO-3-METHYL-1-(TOLUENE-4- SULFONYL)-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2024-10-24 | — | — | US | disclosed |
| CN-118139845-A | Process for the preparation of 5-fluoro-4-imino-3-methyl-1- (toluene-4-sulfonyl) -3, 4-dihydro-1H-pyrimidin-2-one | 安道麦马克西姆有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3862347-A1 | PROCESSES FOR THEIR PREPARATION OF 5-FLUORO-4-IMINO-3-(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)- 3,4-DIHYDROPYRIMIDIN-2(1H)-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2021-08-11 | — | — | EP | disclosed |
| EP-3862346-A1 | PROCESSES FOR THE PREPARATION OF 5-FLUORO-4-IMINO-3-(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)- 3,4-DIHYDROPYRIMIDIN-2(1H)-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2021-08-11 | — | — | EP | disclosed |
| EP-3862346-A1 | PROCESSES FOR THE PREPARATION OF 5-FLUORO-4-IMINO-3-(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)- 3,4-DIHYDROPYRIMIDIN-2(1H)-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2021-08-11 | — | — | EP | disclosed |
| EP-3862347-A1 | PROCESSES FOR THEIR PREPARATION OF 5-FLUORO-4-IMINO-3-(ALKYL/SUBSTITUTED ALKYL)-1-(ARYLSULFONYL)- 3,4-DIHYDROPYRIMIDIN-2(1H)-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2021-08-11 | — | — | EP | disclosed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| WO-2014105845-A1 | 3-ALKYL-5-FLUORO-4-SUBSTITUTED-IMINO-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-07-03 | — | — | WO | disclosed |
| EP-2462134-B1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
| WO-2011017547-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240351990-A1 | PROCESS FOR PREPARING 5-FLUORO-4-IMINO-3-METHYL-1-(TOLUENE-4- SULFONYL)-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE | AFF4, AFF1, WASHC5 | MEN1 1039/4885KMT2A 1200/4885MAPT 2372/4885 |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DDT, SULT1E1, CYP1A1 | MEN1 741/4885KMT2A 2775/4885MAPT 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.