Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010844 | 0.83 | CA1 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12900477 | 0.83 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7016019 | 0.75 | L3MBTL1 (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31052299 | 0.74 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30120753 | 0.73 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12696218 | 0.72 | CA1 (0.49) | MEN1KMT2AMAPTALDH1A1NOD1 | |
| SCHEMBL31052310 | 0.72 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12900467 | 0.71 | DCK (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL31006563 | 0.71 | L3MBTL1 (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29283857 | 0.71 | L3MBTL1 (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |