Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761711 | 0.78 | MEN1 (0.32) | MAPTALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL9128991 | 0.76 | MAPT (0.39) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL8855149 | 0.75 | MEN1 (0.35) | MAPTALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL322239 | 0.75 | MEN1 (0.35) | MAPTALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL2919461 | 0.75 | MAPT (0.52) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL10437518 | 0.74 | GPR3 (0.35) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL6716159 | 0.73 | RUNX1 (0.34) | MAPTALDH1A1NSD2GAATP53 | |
| SCHEMBL981109 | 0.72 | TSHR (0.39) | MAPTALDH1A1TDP1GAATSHR | |
| SCHEMBL3749658 | 0.72 | CYP1A2 (0.42) | MAPTALDH1A1LMNATDP1TSHR | |
| SCHEMBL3754783 | 0.72 | MAPT (0.36) | MAPTALDH1A1L3MBTL1NSD2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688424-B1 | PHOSPHONIUM BORATE COMPOUND AND METHOD OF USING THE SAME | HOKKO CHEM IND CO (JP) | 2016-01-13 | — | — | EP | claimed |
| US-20170267836-A1 | Process For Preparing Ethylenedialkylphosphinic Acids, Esters And Salts And Use Thereof | CLARIANT PLASTICS & COATINGS LTD (CH) | 2017-09-21 | — | — | US | disclosed |
| EP-3197895-A1 | NOVEL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| EP-2379575-B1 | HYDROPHOSPHORYLATION OF PHOSPHONIC ACID DERIVATIVES TO YIELD FLAME RETARDANTS | CLARIANT INT LTD (CH) | 2017-04-12 | — | — | EP | disclosed |
| WO-2016046241-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-03-31 | — | — | WO | disclosed |
| US-9279085-B2 | Method for the production of monofunctionalized dialkylphosphinic acids, esters and salts, and use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2016-03-08 | — | — | US | disclosed |
| EP-1688424-B1 | PHOSPHONIUM BORATE COMPOUND AND METHOD OF USING THE SAME | HOKKO CHEM IND CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-2379572-B1 | METHOD FOR THE PRODUCTION OF MONOFUNCTIONALIZED DIALKYLPHOSPHINIC ACIDS, ESTERS, AND SALTS, AND USE THEREOF | CLARIANT INT LTD (CH) | 2015-12-23 | — | — | EP | disclosed |
| US-9181487-B2 | Process for preparing ethylenedialkylphosphinic acids, esters and salts by means of acetylene and use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-11-10 | — | — | US | disclosed |
| US-9139714-B2 | Method for producing dialkylphosphinic acids and esters and salts thereof by means of allyl alcohols-acroleins and use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-09-22 | — | — | US | disclosed |
| US-20070098616-A1 | Process for producing phosponium borate compound, novel phosphonium borate compound, and method of using the same | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1688424-A1 | PROCESS FOR PRODUCING PHOSPHONIUM BORATE COMPOUND, NOVEL PHOSPHONIUM BORATE COMPOUND, AND METHOD OF USING THE SAME | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOLLO CHEMICAL INDUSTRY CO., LTD (JP) | 2006-01-26 | — | — | US | disclosed |
| CN-1628122-A | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOKKO CHEM IND CO (JP) | 2005-06-15 | — | — | CN | disclosed |
| EP-1473297-A1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-4341894-A | 2,4,6 TRI-SUBSTITUTED PYRYLIUM DYE SALTS | EASTMAN KODAK COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| US-4167412-A | COMPRISING A PYRYLIUM OR THIOPYRYLIUM SALT | EASTMAN KODAK COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HRH3, HRH4, HRH1 | MAPT 4358/4885ALDH1A1 1764/4885L3MBTL1 682/4885 |
| US-20170267836-A1 | Process For Preparing Ethylenedialkylphosphinic Acids, Esters And Salts And Use Thereof | ENPP1, ENPP3, FADS2 | MAPT 3964/4885ALDH1A1 983/4885L3MBTL1 4533/4885 |
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | MAPT 4838/4885ALDH1A1 3508/4885L3MBTL1 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.