Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015205 | 0.80 | L3MBTL1 (0.57) | MAPTSMN1; SMN2HSD17B10ALDH1A1HTR7 | |
| SCHEMBL7017298 | 0.76 | TP53 (0.46) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL7021271 | 0.76 | CYP19A1 (0.41) | MAPTSMN1; SMN2KMT2AHSD17B13LMNA | |
| SCHEMBL7016056 | 0.75 | THRB (0.47) | MAPTSMN1; SMN2ALDH1A1KMT2AHSD17B13 | |
| Morpholine SCHEMBL7015362 | 0.74 | NPSR1 (0.36) | MAPTSMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL7019393 | 0.74 | HTT (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7008880 | 0.73 | TP53 (0.37) | MAPTSMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7015357 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL7020188 | 0.68 | LMNA (0.46) | MAPTSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL7015987 | 0.66 | TP53 (0.47) | MAPTSMN1; SMN2HSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |