Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016853 | 0.80 | MLYCD (0.43) | TP53CXCR3MLYCDMEN1GAA | |
| SCHEMBL7020798 | 0.79 | KCNH2 (0.50) | TP53CXCR3MLYCD | |
| SCHEMBL17586324 | 0.77 | PIK3CD (0.52) | TP53CXCR3POLBMEN1NPC1 | |
| SCHEMBL7147051 | 0.77 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL7017597 | 0.77 | CXCR3 (0.44) | TP53CXCR3MLYCD | |
| SCHEMBL7100648 | 0.76 | CXCR3 (0.44) | CXCR3MLYCDNPC1RAB9A | |
| SCHEMBL7017817 | 0.75 | ALDH1A1 (0.50) | TP53CXCR3MEN1NPC1RAB9A | |
| SCHEMBL17586323 | 0.75 | PIK3CD (0.50) | CXCR3POLBMEN1NPC1GAA | |
| SCHEMBL7020727 | 0.74 | TP53 (0.41) | TP53POLBRORC | |
| SCHEMBL15817107 | 0.72 | PIK3CD (0.52) | CXCR3MEN1NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |