Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 11/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017597 | 0.85 | CXCR3 (0.44) | MLYCDCXCR3TP53ALDH1A1MAPK1 | |
| SCHEMBL7020798 | 0.85 | KCNH2 (0.50) | MLYCDCXCR3TP53 | |
| SCHEMBL7100648 | 0.84 | CXCR3 (0.44) | MLYCDCXCR3ALDH1A1 | |
| SCHEMBL7020723 | 0.80 | TP53 (0.43) | MLYCDCXCR3TP53MEN1GAA | |
| SCHEMBL7016812 | 0.79 | TP53 (0.46) | TP53KDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL7018385 | 0.79 | TP53 (0.46) | TP53ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL7100250 | 0.78 | MEN1 (0.60) | TP53ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL7014520 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPK1MEN1CYP1A2 | |
| SCHEMBL7023261 | 0.76 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPK1MEN1CYP1A2 | |
| SCHEMBL7013767 | 0.75 | LMNA (0.53) | ALDH1A1MAPK1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |