SCHEMBL7021047

SCHEMBL7021047

CCCC1=C(C(=O)O)C(c2cccc3c2OCC=C3)c2c[nH]nc2N1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.31
AMY1A P0DUB6 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6292511 0.90 GAA (0.41) MGAMAMY1AGAASIMGAM2
SCHEMBL6297341 0.81 MGAM (0.32) MGAMAMY1AGAASIMGAM2
SCHEMBL7435806 0.77 MEN1 (0.39)
SCHEMBL7017886 0.77 CACNA1D (0.31)
SCHEMBL7429502 0.77 CYP2C9 (0.42) GAA
SCHEMBL7441431 0.76 PYGL (0.39) GAA
SCHEMBL7433747 0.76 ALDH1A1 (0.37)
SCHEMBL6293408 0.76 CYP1A2 (0.42)
SCHEMBL7018953 0.75 GAA (0.41) GAA
SCHEMBL7434003 0.75 CACNA1D (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1355909-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2003-10-29 EP disclosed
WO-2002062795-A9 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORP (JP) 2002-10-10 WO disclosed
WO-2002062795-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORPORATION (JP) 2002-08-15 WO disclosed