Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.45 |
| ▸ | ABAT | P80404 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dinitrophenol SCHEMBL27991650 | 0.98 | GPR35 (0.70) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| SCHEMBL8959273 | 0.88 | GPR35 (0.72) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| 2,4-Dinitrophenol SCHEMBL27564362 | 0.87 | GPR35 (0.66) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| 2,4-Dinitrophenol SCHEMBL28256921 | 0.87 | GPR35 (0.66) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| Trinitrophenol SCHEMBL10727440 | 0.86 | GPR35 (0.74) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| 2,4-Dinitrophenol SCHEMBL5866337 | 0.85 | GPR35 (0.79) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| 2,4-Dinitrophenol SCHEMBL16980 | 0.85 | GPR35 (0.52) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| 2,4-Dinitrophenol SCHEMBL27905661 | 0.85 | ALDH1A1 (0.85) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| Trinitrophenol SCHEMBL9314438 | 0.85 | GPR35 (0.68) | GPR35ALDH1A1TSHRMAPK1HPGD | |
| SCHEMBL29516730 | 0.85 | GPR35 (1.00) | GPR35ALDH1A1TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030045556-A1 | Aryl-N-cyanoguanidines and methods related thereto | MITOKOR (US) | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045556-A1 | Aryl-N-cyanoguanidines and methods related thereto | COX5A, COX5B, MT-CO1 | GPR35 611/4885ALDH1A1 320/4885TSHR 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.