Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286636 | 0.85 | L3MBTL1 (0.43) | RAB9ATP53L3MBTL1KIF11NPC1 | |
| SCHEMBL17368411 | 0.78 | KIF11 (0.58) | RAB9ATP53L3MBTL1TDP1KIF11 | |
| SCHEMBL178373 | 0.76 | CYP17A1 (0.54) | RAB9ATP53TDP1KIF11POLB | |
| SCHEMBL4110532 | 0.74 | L3MBTL1 (0.83) | RAB9AL3MBTL1TDP1KIF11KDM4E | |
| SCHEMBL18086475 | 0.72 | L3MBTL1 (0.59) | RAB9ATP53L3MBTL1TDP1KIF11 | |
| SCHEMBL18644906 | 0.71 | RAB9A (0.55) | RAB9ATP53L3MBTL1TDP1KIF11 | |
| Hydrochloric Acid SCHEMBL27171218 | 0.70 | TSHR (0.39) | RAB9ATP53KIF11HDAC1NPC1 | |
| SCHEMBL31150303 | 0.70 | DGAT1 (0.45) | — | |
| SCHEMBL23966382 | 0.70 | HPGD (0.53) | RAB9AL3MBTL1TDP1NPC1MAPK14 | |
| SCHEMBL8200423 | 0.69 | L3MBTL1 (0.67) | RAB9AL3MBTL1TDP1KIF11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |