Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541881 | 0.85 | EPHX1 (0.52) | EPHX1NAAAALDH1A1MAPTHTT | |
| SCHEMBL6658383 | 0.85 | EPHX1 (0.47) | EPHX1NAAAHTTCYP19A1SMN1; SMN2 | |
| SCHEMBL9292325 | 0.85 | EPHX1 (0.45) | EPHX1NAAAALDH1A1HTTTSHR | |
| SCHEMBL1999691 | 0.84 | EPHX1 (0.47) | EPHX1NAAAALDH1A1HTTTSHR | |
| SCHEMBL317579 | 0.84 | NAAA (0.47) | EPHX1NAAAALDH1A1MAPTHTT | |
| SCHEMBL23749099 | 0.83 | EPHX1 (0.43) | EPHX1NAAAHTTCYP19A1CYP2C19 | |
| SCHEMBL28992582 | 0.82 | NAAA (0.46) | EPHX1NAAAALDH1A1MAPTHTT | |
| SCHEMBL7814661 | 0.81 | EPHX1 (0.47) | EPHX1NAAAALDH1A1MAPTHTT | |
| Ethyl Acetate SCHEMBL28105314 | 0.80 | ALDH1A1 (0.45) | EPHX1NAAAALDH1A1HTTTSHR | |
| SCHEMBL28757900 | 0.80 | EPHX1 (0.44) | EPHX1NAAAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231288-A1 | IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2021-11-18 | — | — | WO | claimed |
| WO-2021162938-A1 | COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM | SIRRUS, INC. (US) | 2021-08-19 | — | — | WO | claimed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| CN-107075037-B | Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof | 赛鲁斯股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | claimed |
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2019-06-04 | — | — | US | claimed |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| US-20220192963-A1 | METHODS OF CURING DICARBONYL SUBSTITUTED-1-ALKENES | SIRRUS INC (US) | 2022-06-23 | — | — | US | disclosed |
| US-20220153932-A1 | PREPOLYMERS OF 1,1-DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER | SIRRUS INC (US) | 2022-05-19 | — | — | US | disclosed |
| US-20220112151-A1 | COMPOSITIONS OF DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER | SIRRUS INC (US) | 2022-04-14 | — | — | US | disclosed |
| WO-2021231288-A1 | IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021183340-A1 | RADIATION CURED COPOLYMERS OF DICARBONYL SUBSTITUTED-L-ALKENES AND ELECTRON RICH COMONOMERS | SIRRUS, INC. (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021162938-A1 | COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM | SIRRUS, INC. (US) | 2021-08-19 | — | — | WO | disclosed |
| WO-2019060188-A1 | CATALYTIC CYCLE FOR PRODUCTION OF 1,1-DISUBSTITUTED ALKENES | SIRRUS, INC. (US) | 2019-03-28 | — | — | WO | disclosed |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-3191533-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |
| EP-0843220-B1 | Radiation sensitive resin composition | JSR CORP (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-5994022-A | BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID | JSR CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0843220-A1 | Radiation sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | PCBP1, PARG, PARP1 | EPHX1 2622/4885NAAA 2267/4885ALDH1A1 121/4885 |
| US-20220112151-A1 | COMPOSITIONS OF DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER | PARG, PARN, LIG1 | EPHX1 3819/4885NAAA 2138/4885ALDH1A1 274/4885 |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | PCBP1, PARG, PARP1 | EPHX1 2622/4885NAAA 2267/4885ALDH1A1 121/4885 |
| US-20220153932-A1 | PREPOLYMERS OF 1,1-DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER | PLOD1, COL1A1, PLOD2 | EPHX1 2428/4885NAAA 2542/4885ALDH1A1 313/4885 |
| US-20220192963-A1 | METHODS OF CURING DICARBONYL SUBSTITUTED-1-ALKENES | CDH1, KDM1A, ALKBH3 | EPHX1 3277/4885NAAA 349/4885ALDH1A1 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.