Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745829 | 0.81 | PIK3CA (0.45) | ACACBPIK3CAMTOR | |
| SCHEMBL7035423 | 0.81 | RAD52 (0.47) | MAPTGAAKDM4ERAD52ALDH1A1 | |
| SCHEMBL7037508 | 0.77 | MAPT (0.43) | MAPTGFERGAAALDH1A1KMT2A | |
| SCHEMBL24746474 | 0.76 | CHRNB2 (0.38) | ACACBLIPCLIPGPIK3CAMTOR | |
| SCHEMBL17888570 | 0.75 | MEN1 (0.39) | MAPTGFERGAAKDM4ESMN1; SMN2 | |
| SCHEMBL13280086 | 0.74 | OPRD1 (0.42) | ACACB | |
| SCHEMBL25900569 | 0.73 | MAPT (0.40) | MAPTGFERGAAKDM4ESMN1; SMN2 | |
| SCHEMBL19297613 | 0.73 | LIPG (0.46) | MAPTKDM4EKMT2ARECQLACACB | |
| SCHEMBL2126264 | 0.71 | KDM4E (0.38) | MAPTGFERGAAKDM4ESMN1; SMN2 | |
| SCHEMBL2127940 | 0.70 | KDM4E (0.35) | MAPTGFERGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| EP-1185236-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2002-03-13 | — | — | EP | claimed |
| WO-2001041724-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2001-06-14 | — | — | WO | claimed |
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| EP-1185236-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001041724-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | KRT18, CDC73, AOC1 | MAPT 1146/4885GFER 1850/4885GAA 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.