SCHEMBL7039010

SCHEMBL7039010

CN1C(=O)C=C(c2ccccc2C2=CC(=O)N(C)C2=O)C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
CASP3 P42574 1/20 0.47
TTR P02766 2/20 0.45
CES1 P23141 2/20 0.45
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CDC25B P30305 2/20 0.40
TP53 P04637 1/20 0.40
MAPK10 P53779 1/20 0.40
CA9 Q16790 2/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.37
PTPRC P08575 2/20 0.37
TRPA1 O75762 1/20 0.36
MTOR P42345 1/20 0.36
PTPRF P10586 1/20 0.35
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20261788 0.88 MAPT (0.48) MAPTCASP3TTRCES1ALDH1A1
SCHEMBL149927 0.81 MAPT (0.53) MAPTCASP3ALDH1A1CDC25BPTPRC
Ethane SCHEMBL8564354 0.79 MAPT (0.51) MAPTCASP3ALDH1A1CDC25BPTPRC
SCHEMBL27616714 0.77 PTPRC (0.58) PTPRC
SCHEMBL5879168 0.76 SIRT2 (0.63) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL4194511 0.72 HSD11B1 (0.45) MAPTMEN1KMT2ATP53POLB
SCHEMBL4190224 0.72 AKR1B1 (0.37) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL10994041 0.71 RGS4 (0.53) MAPTALDH1A1NPC1RAB9AKDM4E
SCHEMBL28263 0.71 CASP3 (0.81) MAPTCASP3TTRCES1ALDH1A1
SCHEMBL29511191 0.71 CASP3 (0.81) MAPTCASP3TTRCES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881271-B1 Vibration absorbing, heat resistant, pressure sensitive acrylic adhesive composition and the adhesive tape made from it LOHMANN GMBH & CO KG (DE) 2003-03-26 EP claimed
EP-0881271-A1 Vibration absorbing, heat resistant, pressure sensitive acrylic adhesive composition and the adhesive tape made from it Lohmann GmbH & Co. KG (DE) 1998-12-02 EP claimed