Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ATF4 | P18848 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613422 | 0.78 | PKM (0.43) | HPGDHTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17938412 | 0.77 | ALDH1A1 (0.50) | RAB9AALDH1A1TSHR | |
| SCHEMBL19134233 | 0.76 | LMNA (0.72) | HPGDHTTRAB9ALMNAATF4 | |
| SCHEMBL11453756 | 0.75 | RAB9A (0.47) | HPGDHTTRAB9AALDH1A1KMT2A | |
| SCHEMBL902241 | 0.74 | ALOX15 (0.53) | HPGDLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6611585 | 0.74 | LMNA (0.68) | HPGDHTTRAB9ALMNAATF4 | |
| SCHEMBL11453752 | 0.73 | SMN1; SMN2 (0.42) | HPGDHTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL2565533 | 0.73 | KMT2A (0.40) | HTTLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11850746 | 0.73 | KMT2A (0.39) | HPGDRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1803317 | 0.73 | KDM4E (0.46) | HPGDHTTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |