Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613422 | 0.81 | PKM (0.43) | SMN1; SMN2MEN1KMT2APOLBHTT | |
| SCHEMBL2565533 | 0.76 | KMT2A (0.40) | SMN1; SMN2MEN1KMT2APOLBLMNA | |
| SCHEMBL11850746 | 0.76 | KMT2A (0.39) | SMN1; SMN2KMT2APOLBUSP2RAB9A | |
| SCHEMBL1803317 | 0.76 | KDM4E (0.46) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL11453756 | 0.75 | RAB9A (0.47) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL902241 | 0.74 | ALOX15 (0.53) | SMN1; SMN2MEN1KMT2APOLBLMNA | |
| SCHEMBL7044039 | 0.73 | HPGD (0.56) | SMN1; SMN2MAPK1MEN1KMT2APOLB | |
| SCHEMBL7048126 | 0.73 | HSD11B1 (0.35) | SMN1; SMN2POLBRECQLTSHRRAB9A | |
| SCHEMBL27673182 | 0.73 | LMNA (0.53) | MEN1KMT2ALMNATSHRRAB9A | |
| SCHEMBL8749612 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182911-A | BETA-ADRENERGIC BLOCKING AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-01-08 | — | — | US | disclosed |