Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204645 | 0.89 | ALDH1A1 (0.74) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL1323562 | 0.84 | MAPT (0.70) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL14406408 | 0.83 | KMT2A (0.64) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL6567228 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL7044479 | 0.80 | LMNA (0.56) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL7038965 | 0.79 | LMNA (0.64) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL11332800 | 0.78 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL8849533 | 0.77 | LMNA (0.66) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL8849935 | 0.77 | KDM4E (0.53) | ALDH1A1MAPTKDM4EALOX12GAA | |
| SCHEMBL11341636 | 0.77 | ALDH1A1 (0.75) | ALDH1A1MAPTKDM4EALOX12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2003-09-18 | — | — | US | disclosed |
| US-6498191-B2 | FOR TREATMENT OF ALZHEIMER'S DISEASE, DIABETES MELLITUS, PARKINSON'S DISEASE, NEURONAL AND CARDIAC ISCHEMIA, HUNTINGTON'S DISEASE, STROKE | MITOKOR | 2002-12-24 | — | — | US | disclosed |
| EP-1222920-A2 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2002-07-17 | — | — | EP | disclosed |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-06-06 | — | — | US | disclosed |
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | ALDH1A1 945/4885MAPT 284/4885KDM4E 4364/4885 |
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | ALDH1A1 936/4885MAPT 283/4885KDM4E 4356/4885 |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | ALDH1A1 931/4885MAPT 285/4885KDM4E 4384/4885 |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | ALDH1A1 945/4885MAPT 284/4885KDM4E 4364/4885 |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | ALDH1A1 942/4885MAPT 284/4885KDM4E 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.