Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723991 | 0.80 | TSHR (0.41) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL38015 | 0.80 | CES1 (0.52) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL21811153 | 0.77 | CES2 (0.50) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL5169856 | 0.77 | ALDH1A1 (0.62) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL2722492 | 0.77 | KMT2A (0.39) | CES2CES1LMNAMAPTTSHR | |
| SCHEMBL20659169 | 0.73 | ALDH1A1 (0.43) | CES2CES1ALDH1A1LMNAMAPT | |
| SCHEMBL2722548 | 0.72 | FABP3 (0.41) | ALDH1A1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL2724491 | 0.70 | LMNA (0.49) | LMNATSHRHTTKMT2ACYP3A4 | |
| SCHEMBL3461999 | 0.70 | NPC1 (0.44) | ALDH1A1TSHRACHEHTTNPC1 | |
| SCHEMBL22708495 | 0.69 | MEN1 (0.41) | CES2CES1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2003-09-18 | — | — | US | disclosed |
| US-6511966-B2 | Administering for therapy of mitochondria medited disease | MITOKOR | 2003-01-28 | — | — | US | disclosed |
| US-6498191-B2 | FOR TREATMENT OF ALZHEIMER'S DISEASE, DIABETES MELLITUS, PARKINSON'S DISEASE, NEURONAL AND CARDIAC ISCHEMIA, HUNTINGTON'S DISEASE, STROKE | MITOKOR | 2002-12-24 | — | — | US | disclosed |
| EP-1222920-A2 | Mitochondria protecting agents for treating mitochondria associated diseases | MITOKOR (US) | 2002-07-17 | — | — | EP | disclosed |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-06-06 | — | — | US | disclosed |
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | GHOSH SOUMITRA S (US) | 2002-01-24 | — | — | US | disclosed |
| EP-1051165-A2 | MITOCHONDRIA PROTECTING AGENTS FOR TREATING MITOCHONDRIA ASSOCIATED DISEASES | Mitokor (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037294-A2 | MITOCHONDRIA PROTECTING AGENTS FOR TREATING MITOCHONDRIA ASSOCIATED DISEASES | MITOKOR (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065298-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | CES2 3323/4885CES1 2548/4885ALDH1A1 945/4885 |
| US-20030176448-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | CES2 3285/4885CES1 2536/4885ALDH1A1 936/4885 |
| US-20020068750-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | CES2 3293/4885CES1 2550/4885ALDH1A1 931/4885 |
| US-20020010195-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | CES2 3323/4885CES1 2548/4885ALDH1A1 945/4885 |
| US-20020065299-A1 | Mitochondria protecting agents for treating mitochondria associated diseases | TFAM, HSPA9, HSPD1 | CES2 3299/4885CES1 2587/4885ALDH1A1 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.