Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 4/20 | 0.51 |
| ▸ | AKT1 | P31749 | 4/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.51 |
| ▸ | PRKG2 | Q13237 | 4/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.51 |
| ▸ | GSK3A | P49840 | 4/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.51 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4978745 | 0.95 | SLC6A9 (0.56) | SLC6A9NPC1GSK3BROCK1CLK4 | |
| SCHEMBL7045241 | 0.90 | ALDH1A1 (0.55) | GSK3BROCK1CLK4RPS6KA5AKT1 | |
| SCHEMBL14595548 | 0.90 | NPC1 (0.63) | SLC6A9NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL4978454 | 0.86 | ALDH1A1 (0.54) | GSK3BROCK1CLK4RPS6KA5AKT1 | |
| SCHEMBL7048161 | 0.83 | ALDH1A1 (0.55) | NPC1GSK3BROCK1CLK4RPS6KA5 | |
| SCHEMBL14595547 | 0.81 | LMNA (0.56) | NPC1ALDH1A1KMT2AEPHX2L3MBTL1 | |
| SCHEMBL6707538 | 0.79 | LTA4H (0.47) | SLC6A9NPC1ROCK2ALDH1A1MEN1 | |
| SCHEMBL6707539 | 0.79 | ALDH1A1 (0.48) | GSK3BROCK1CLK4RPS6KA5AKT1 | |
| SCHEMBL4450456 | 0.76 | NPC1 (0.64) | SLC6A9NPC1ALDH1A1GAACA1 | |
| SCHEMBL4097730 | 0.76 | LTA4H (0.44) | MEN1KMT2AMAPKAPK2GAALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | FRANTZ DOUG E (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | AADAC, ACAA2, ACSS2 | SLC6A9 2352/4885NPC1 2263/4885GSK3B 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.