Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.52 |
| ▸ | PRKACA | P17612 | 3/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | GSK3A | P49840 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.52 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.52 |
| ▸ | SGK2 | Q9HBY8 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045241 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ROCK2ROCK1PRKG1 | |
| SCHEMBL7047478 | 0.83 | SLC6A9 (0.56) | ALDH1A1GAAROCK2ROCK1PRKG1 | |
| SCHEMBL4978454 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CYP3A4ROCK2ROCK1PRKG1 | |
| SCHEMBL12087551 | 0.79 | CYP1A2 (0.49) | ALDH1A1CYP3A4GAACYP2D6CYP2C9 | |
| SCHEMBL6707539 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP3A4ROCK2ROCK1PRKG1 | |
| SCHEMBL4978745 | 0.78 | SLC6A9 (0.56) | ALDH1A1CYP3A4GAAROCK2ROCK1 | |
| SCHEMBL14595547 | 0.78 | LMNA (0.56) | ALDH1A1CYP3A4S1PR3KMT2ANPC1 | |
| SCHEMBL12217089 | 0.78 | SMN1; SMN2 (0.43) | CYP3A4GAAROCK2ROCK1PRKG1 | |
| SCHEMBL28476592 | 0.77 | ALDH1A1 (0.86) | ALDH1A1CYP3A4GAAMEN1KMT2A | |
| SCHEMBL6222897 | 0.76 | KMT2A (0.82) | ALDH1A1CYP3A4GAAMAPK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | FRANTZ DOUG E (US) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083503-A1 | Synthesis of acylated keto amides from sulfonyl amides | AADAC, ACAA2, ACSS2 | ALDH1A1 512/4885CYP3A4 1159/4885GAA 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.