Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562389 | 0.77 | RHEB (0.36) | LOXL2 | |
| SCHEMBL189125 | 0.77 | LOXL2 (0.37) | LOXL2 | |
| SCHEMBL29093628 | 0.77 | LOXL2 (0.58) | LOXL2DPP4 | |
| SCHEMBL5178946 | 0.74 | MTNR1A (0.36) | LOXL2 | |
| SCHEMBL694595 | 0.74 | ADORA1 (0.39) | LOXL2 | |
| SCHEMBL9074352 | 0.72 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL1661482 | 0.71 | SIRT1 (0.42) | LOXL2 | |
| SCHEMBL5778675 | 0.71 | RHEB (0.37) | LOXL2 | |
| SCHEMBL6587779 | 0.71 | F2 (0.51) | LOXL2 | |
| SCHEMBL188218 | 0.70 | GAA (0.35) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421823-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| WO-2010124086-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |
| EP-2421823-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010124086-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | disclosed |