SCHEMBL7048560

SCHEMBL7048560

CC(C)C[C@H](NC(=O)C1CCNCC1)C(=O)N[C@@H](CCc1ccccc1)C(=O)c1nc2ccccc2o1

nearest known ligand 0.82

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSS P25774 16/20 0.82
CTSL P07711 2/20 0.82
CTSB P07858 2/20 0.82
CTSK P43235 2/20 0.82
PRSS8 Q16651 2/20 0.47
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463725 0.92 CTSS (0.82) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7046650 0.92 CTSS (0.81) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7112197 0.90 CTSL (1.00) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7045280 0.89 CTSS (1.00) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7042873 0.87 CTSS (0.64) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7045320 0.87 CTSS (0.64) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL7046653 0.87 CTSK (0.72) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL29669787 0.87 CTSK (0.72) CTSSCTSLCTSBCTSKPRSS8
Hydrochloric Acid SCHEMBL6064381 0.87 CTSS (0.63) CTSSCTSLCTSBCTSKPRSS8
SCHEMBL6061819 0.83 CTSS (0.61) CTSSCTSLCTSBCTSKPRSS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584118-B2 Cas9 variants and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-24 US disclosed
US-12559737-B2 Cas9 variants and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-02-24 US disclosed
US-20250171684-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2025-05-29 US disclosed
CN-119236966-A Crude ethylene glycol hydrofining method and hydrofining agent 中国石油化工股份有限公司 2025-01-03 CN disclosed
EP-4482843-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2025-01-01 EP disclosed
WO-2023161168-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-31 WO disclosed
CN-116455375-A One-key power on-off control circuit with low power consumption and low cost 恒科科技产业有限公司 2023-07-18 CN disclosed
US-20230056852-A1 CAS9 VARIANTS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-02-23 US disclosed
CN-109069573-B Single domain antibodies that bind CD20 弗拉芒区生物技术研究所 2022-04-05 CN disclosed
US-20030232864-A1 Novel Compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. (US) 2003-12-18 US disclosed
US-6576630-B1 Alkanoyl substituted benzooxazoles or naphthooxazoles AXYS PHARMACEUTICALS, INC. 2003-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584118-B2 Cas9 variants and uses thereof RNGTT, CPSF7, CPSF1 CTSS 367/4885CTSL 799/4885CTSB 1447/4885
US-20250171684-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES AHR, PAH, DDT CTSS 2224/4885CTSL 4094/4885CTSB 3407/4885
US-12559737-B2 Cas9 variants and uses thereof TPR, INTS9, CPSF1 CTSS 759/4885CTSL 1038/4885CTSB 2089/4885
US-20030232864-A1 Novel Compounds and compositions as protease inhibitors SERPINB1, CTRL, CTSZ CTSS 9/4885CTSL 18/4885CTSB 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.