Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244847 | 0.89 | KDM4E (0.66) | PTPN5MAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL7020296 | 0.87 | MAPT (0.57) | MAPTSMN1; SMN2TP53MAPK1KDM4E | |
| SCHEMBL6234637 | 0.87 | MAPT (0.69) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL6238938 | 0.85 | KMT2A (0.56) | MAPTSMN1; SMN2TP53LMNAKDM4E | |
| SCHEMBL6431684 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2TP53LMNAKDM4E | |
| SCHEMBL7019254 | 0.83 | ALDH1A1 (0.48) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL7191192 | 0.82 | ALDH1A1 (0.60) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL7634269 | 0.81 | ALDH1A1 (0.49) | MAPTSMN1; SMN2TP53LMNAMAPK1 | |
| SCHEMBL4254375 | 0.80 | ALDH1A1 (0.72) | MAPTSMN1; SMN2TP53LMNAKDM4E | |
| SCHEMBL6510914 | 0.79 | KDM4E (0.65) | MAPTSMN1; SMN2TP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078276-A1 | Matrix metalloproteinase inhibitors | ANDRIANJARA CHARLES (FR) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078276-A1 | Matrix metalloproteinase inhibitors | MMP13, MMP25, MMP12 | PTPN5 3656/4885MAPT 2607/4885SMN1; SMN2 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.