Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076839 | 0.84 | KMT2A (0.59) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL7071891 | 0.83 | THRB (0.63) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL7652755 | 0.81 | MAPT (0.59) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL7075151 | 0.81 | HDAC4 (0.49) | THRBMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3074024 | 0.80 | DGAT1 (0.58) | THRBMAPTPOLBDGAT1LMNA | |
| SCHEMBL7075210 | 0.80 | THRB (0.57) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL7074028 | 0.80 | MAPT (0.62) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL15188835 | 0.79 | KMT2A (0.67) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL7075110 | 0.78 | LMNA (0.49) | THRBMAPTPOLBMEN1KMT2A | |
| SCHEMBL7074179 | 0.78 | MAPT (0.74) | THRBMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |