Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652755 | 0.86 | MAPT (0.59) | LMNAPOLBMAPTTHRBMEN1 | |
| SCHEMBL7071592 | 0.84 | LMNA (0.50) | LMNAPOLBMAPTHPGDHTT | |
| SCHEMBL7074156 | 0.84 | LMNA (0.55) | LMNAPOLBMAPTHPGDHTT | |
| SCHEMBL7070051 | 0.82 | LMNA (0.52) | LMNAPOLBMAPTHPGDHTT | |
| SCHEMBL7076643 | 0.81 | LMNA (0.53) | LMNAPOLBMAPTHPGDHTT | |
| SCHEMBL7076839 | 0.80 | KMT2A (0.59) | LMNAPOLBMAPTTHRBMEN1 | |
| SCHEMBL7074841 | 0.79 | KMT2A (0.45) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL7070001 | 0.78 | THRB (0.63) | LMNAPOLBMAPTHTTTHRB | |
| SCHEMBL7072193 | 0.78 | GAA (0.45) | LMNAPOLBMAPTHPGDHTT | |
| SCHEMBL7075151 | 0.77 | HDAC4 (0.49) | LMNAMAPTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |