Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077928 | 0.86 | NPY1R (0.39) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7074301 | 0.85 | AOC3 (0.39) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7077874 | 0.79 | F2 (0.46) | ALDH1A1F2F10PRSS1 | |
| SCHEMBL7079112 | 0.78 | F10 (0.41) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7079158 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1F2F10PRSS1L3MBTL1 | |
| SCHEMBL7077585 | 0.74 | F2 (0.41) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7130131 | 0.73 | ITGB3 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL8357377 | 0.73 | ALDH1A1 (0.44) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL7162980 | 0.71 | ITGB3 (0.36) | LMNA | |
| SCHEMBL7073376 | 0.71 | ALDH1A1 (0.46) | ALDH1A1F2F10PRSS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |