Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075687 | 0.92 | BDKRB1 (0.34) | F10F2PRSS1MMP9BDKRB1 | |
| SCHEMBL7079307 | 0.92 | BDKRB1 (0.34) | F10F2PRSS1MMP9BDKRB1 | |
| SCHEMBL7076145 | 0.92 | BDKRB1 (0.34) | F10F2PRSS1MMP9BDKRB1 | |
| SCHEMBL7074301 | 0.79 | AOC3 (0.39) | F10F2PRSS1KMT2AALDH1A1 | |
| SCHEMBL7073328 | 0.78 | ALDH1A1 (0.40) | F10F2PRSS1KMT2ABDKRB1 | |
| SCHEMBL7077874 | 0.78 | F2 (0.46) | F10F2PRSS1MMP9ALDH1A1 | |
| SCHEMBL7077928 | 0.78 | NPY1R (0.39) | F10F2PRSS1KMT2AALDH1A1 | |
| SCHEMBL7079158 | 0.77 | SMN1; SMN2 (0.43) | F10F2PRSS1KMT2AALDH1A1 | |
| SCHEMBL7074971 | 0.77 | GABBR2 (0.34) | MMP9BDKRB1ALDH1A1MMP2MMP8 | |
| SCHEMBL7077585 | 0.74 | F2 (0.41) | F10F2PRSS1MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |