Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074301 | 0.95 | AOC3 (0.39) | NPY1RF2F10PRSS1ALDH1A1 | |
| SCHEMBL8357377 | 0.87 | ALDH1A1 (0.44) | NPY1RF2F10PRSS1ALDH1A1 | |
| SCHEMBL7073328 | 0.86 | ALDH1A1 (0.40) | F2F10PRSS1ALDH1A1KMT2A | |
| SCHEMBL7077670 | 0.81 | LMNA (0.44) | ALDH1A1MAPTKMT2AMCL1NPC1 | |
| SCHEMBL7079112 | 0.78 | F10 (0.41) | F2F10PRSS1ALDH1A1KMT2A | |
| SCHEMBL7077874 | 0.77 | F2 (0.46) | F2F10PRSS1ALDH1A1 | |
| SCHEMBL7079158 | 0.75 | SMN1; SMN2 (0.43) | F2F10PRSS1ALDH1A1MAPT | |
| SCHEMBL7131622 | 0.74 | MMP2 (0.33) | ALDH1A1KMT2AAOC3LMNAATM | |
| SCHEMBL7077585 | 0.72 | F2 (0.41) | F2F10PRSS1ALDH1A1KMT2A | |
| SCHEMBL8359555 | 0.72 | POLB (0.46) | NPY1RMAPTKMT2AMCL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |