Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 15/20 | 0.42 |
| ▸ | FCER2 | P06734 | 5/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 8/20 | 0.40 |
| ▸ | MMP8 | P22894 | 7/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983227 | 0.81 | MMP1 (0.54) | MMEMMP1FCER2MMP3MMP8 | |
| SCHEMBL7424124 | 0.74 | MMP1 (0.68) | MMP1FCER2BIRC2MMP3MMP8 | |
| SCHEMBL7068105 | 0.72 | EPHX2 (0.47) | MME | |
| SCHEMBL7073462 | 0.69 | HPGD (0.40) | — | |
| SCHEMBL7135100 | 0.69 | MME (0.48) | MMEMMP1FCER2MMP8MMP9 | |
| SCHEMBL7424119 | 0.68 | PSMB5 (0.44) | MMP1 | |
| SCHEMBL8386199 | 0.67 | CTSL (0.62) | — | |
| SCHEMBL8387494 | 0.67 | CA2 (0.61) | — | |
| SCHEMBL7069878 | 0.67 | MMP1 (0.34) | MMP1MMP3 | |
| SCHEMBL7066414 | 0.66 | CTSD (0.44) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |