Ethionine

Ethionine

SCHEMBL7073863

CCSCC[C@@H](N)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 11/20 0.63
BHMT2 Q9H2M3 1/20 0.63
NOS2 P35228 2/20 0.58
NOS3 P29474 1/20 0.58
NOS1 P29475 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethionine SCHEMBL8967 1.00 BHMT (0.63) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL8966 1.00 BHMT (0.63) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL11571773 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL28999714 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL31567824 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL3348592 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL11572299 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL28989455 0.98 BHMT (0.61) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL31087565 0.96 BHMT (0.59) BHMTBHMT2NOS2NOS3NOS1
Ethionine SCHEMBL29926199 0.96 BHMT (0.59) BHMTBHMT2NOS2NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11274126-B2 pH-sensitive cyclic peptides UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-03-15 US claimed
CN-105264064-B O-phosphoserine export proteins and methods of producing O-phosphoserine using the same CJ第一制糖株式会社 2020-08-18 CN claimed
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-25 US claimed
WO-2017189860-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-11-02 WO claimed
US-9718921-B2 Amphiphilic derivatives of thioether containing block copolypeptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-08-01 US claimed
US-20160002405-A1 AMPHIPHILIC DERIVATIVES OF THIOETHER CONTAINING BLOCK COPOLYPEPTIDES NATIONAL SCIENCE FOUNDATION 2016-01-07 US claimed
EP-2961758-A1 AMPHIPHILIC DERIVATIVES OF THIOETHER CONTAINING BLOCK COPOLYPEPTIDES The Regents of The University of California (US) 2016-01-06 EP claimed
US-20150057433-A1 PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-02-26 US claimed
WO-2014134203-A9 AMPHIPHILIC DERIVATIVES OF THIOETHER CONTAINING BLOCK COPOLYPEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-10-23 WO claimed
WO-2014134203-A1 AMPHIPHILIC DERIVATIVES OF THIOETHER CONTAINING BLOCK COPOLYPEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-09-04 WO claimed
US-20030162732-A1 Combination of aminosugars and cysteine or cysteine derivatives ASTION DEVELOPMENT A/S (DK) 2003-08-28 US claimed
US-20030158118-A1 Combination of cimetidine and cysteine derivatives for treating cancer WEIDNER MORTEN SLOTH (DK) 2003-08-21 US claimed
WO-2003045359-A2 COMBINATION OF CIMETIDINE AND CYSTEINE DERIVATIVES FOR TREATING CANCER ASTION ONCOLOGY APS (DK) 2003-06-05 WO claimed
WO-2003002125-A2 COMBINATION OF AMINOSUGARS AND CYSTEINE OR CYSTEINE DERIVATIVES ASTION A/S (DK) 2003-01-09 WO claimed
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-19 US disclosed
US-12558448-B2 Immobilized pH indicator for biological indicator growth indication SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-02-24 US disclosed
US-12540162-B2 Preparation of functional homocysteine residues in polypeptides and peptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-03 US disclosed
WO-2003045359-A2 COMBINATION OF CIMETIDINE AND CYSTEINE DERIVATIVES FOR TREATING CANCER ASTION ONCOLOGY APS (DK) 2003-06-05 WO disclosed
WO-2003002125-A2 COMBINATION OF AMINOSUGARS AND CYSTEINE OR CYSTEINE DERIVATIVES ASTION A/S (DK) 2003-01-09 WO disclosed
US-4350627-A Biologically active peptides FARMITALIA CARLO ERBA S.P.A. (IT) 1982-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162732-A1 Combination of aminosugars and cysteine or cysteine derivatives CBS, CTH, AADAT BHMT 83/4885BHMT2 14/4885NOS2 570/4885
US-11274126-B2 pH-sensitive cyclic peptides VIP, PHLPP1, PHLPP2 BHMT 3952/4885BHMT2 3892/4885NOS2 2794/4885
US-12558448-B2 Immobilized pH indicator for biological indicator growth indication ALPG, GUSB, HAO2 BHMT 1156/4885BHMT2 3421/4885NOS2 823/4885
US-20030158118-A1 Combination of cimetidine and cysteine derivatives for treating cancer MGMT, CMA1, CYSLTR2 BHMT 204/4885BHMT2 60/4885NOS2 508/4885
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES BHMT2, BHMT, PTMS BHMT 2/4885BHMT2 1/4885NOS2 477/4885
US-12540162-B2 Preparation of functional homocysteine residues in polypeptides and peptides PTMS, AHCY, BHMT2 BHMT 9/4885BHMT2 3/4885NOS2 630/4885
US-20150057433-A1 PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS PTMS, TMT1A, PTMA BHMT 123/4885BHMT2 61/4885NOS2 2246/4885
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS ALPG, UNG, UGDH BHMT 2505/4885BHMT2 3822/4885NOS2 2356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.