Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.52 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073986 | 0.87 | MAPK1 (0.62) | RAB9AALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL7074851 | 0.85 | GAA (0.63) | ALDH1A1TSHRLMNAGAAF2 | |
| Acetic Acid SCHEMBL27550449 | 0.84 | MAPK1 (0.58) | RAB9AALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL7074218 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2MAPK1GAA | |
| SCHEMBL7367810 | 0.80 | RAB9A (0.48) | RAB9AALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL7654785 | 0.80 | YAP1 (0.61) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL7076859 | 0.80 | YAP1 (0.61) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL7075829 | 0.79 | F2 (0.49) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL7074652 | 0.79 | F2 (0.54) | ALDH1A1TSHRSMN1; SMN2GAAF2 | |
| SCHEMBL7074867 | 0.78 | TGM2 (0.55) | ALDH1A1TSHRLMNAGAAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |