Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | MMP8 | P22894 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076145 | 1.00 | BDKRB1 (0.34) | BDKRB1MMP2MMP9MMP8MMP1 | |
| SCHEMBL7075687 | 1.00 | BDKRB1 (0.34) | BDKRB1MMP2MMP9MMP8MMP1 | |
| SCHEMBL7079112 | 0.92 | F10 (0.41) | BDKRB1MMP2MMP9MMP8MMP1 | |
| SCHEMBL7074971 | 0.85 | GABBR2 (0.34) | BDKRB1MMP2MMP9MMP8MMP1 | |
| SCHEMBL10279296 | 0.77 | CA12 (0.40) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7133670 | 0.77 | ITGB3 (0.47) | BDKRB1MMP2MMP9MMP8MMP1 | |
| SCHEMBL7130131 | 0.77 | ITGB3 (0.46) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7080966 | 0.76 | KDR (0.47) | ALDH1A1ATM | |
| SCHEMBL7080988 | 0.76 | ITGB3 (0.44) | ALDH1A1ATML3MBTL1CA12CA1 | |
| SCHEMBL7131622 | 0.76 | MMP2 (0.33) | BDKRB1MMP2MMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |