Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075687 | 0.85 | BDKRB1 (0.34) | MMP2MMP9ALDH1A1BDKRB1MMP1 | |
| SCHEMBL7076145 | 0.85 | BDKRB1 (0.34) | MMP2MMP9ALDH1A1BDKRB1MMP1 | |
| SCHEMBL7079307 | 0.85 | BDKRB1 (0.34) | MMP2MMP9ALDH1A1BDKRB1MMP1 | |
| SCHEMBL7079112 | 0.77 | F10 (0.41) | MMP2MMP9ALDH1A1BDKRB1MMP1 | |
| SCHEMBL8359555 | 0.74 | POLB (0.46) | SMN1; SMN2TP53MAPTMAPK1 | |
| SCHEMBL7080823 | 0.74 | GABBR2 (0.49) | GABBR2GABBR1MMP2ALDH1A1PRMT1 | |
| SCHEMBL8909238 | 0.73 | GABBR2 (0.56) | GABBR2GABBR1MMP2ALDH1A1MMP7 | |
| SCHEMBL7135413 | 0.73 | GRM4 (0.53) | PRMT1HTTSMN1; SMN2TP53MAPK1 | |
| SCHEMBL7078041 | 0.72 | RORC (0.47) | MMP2ALDH1A1CYP2C9NAMPTMMP8 | |
| SCHEMBL7073753 | 0.71 | GABBR2 (0.50) | GABBR2GABBR1MMP2ALDH1A1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |