Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.32 |
| ▸ | FEN1 | P39748 | 5/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | PRKACG | P22612 | 2/20 | 0.31 |
| ▸ | PRKACB | P22694 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079396 | 0.67 | MMP1 (0.39) | ALOX5APFEN1PRKD3PRKCGPRKCB | |
| SCHEMBL2900748 | 0.66 | PLD1 (0.42) | SIGMAR1ALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL11508844 | 0.66 | IKBKB (0.43) | SMN1; SMN2TP53KMT2AALDH1A1LMNA | |
| SCHEMBL1964149 | 0.65 | PLD1 (0.40) | SIGMAR1KMT2AHSD17B10RAB9AALDH1A1 | |
| SCHEMBL16796971 | 0.64 | RIPK1 (0.40) | SIGMAR1RIPK1 | |
| SCHEMBL8499875 | 0.63 | RIPK1 (0.40) | SIGMAR1HSD17B10RIPK1PRMT5WDR77 | |
| SCHEMBL5321655 | 0.63 | RIPK1 (0.40) | SIGMAR1HSD17B10RIPK1 | |
| SCHEMBL31232802 | 0.63 | PLD1 (0.42) | SIGMAR1SMN1; SMN2TP53TSHRKMT2A | |
| SCHEMBL9047401 | 0.63 | SIGMAR1 (0.44) | SIGMAR1ALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL28938508 | 0.63 | HSD11B1 (0.40) | SIGMAR1HSD17B10RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | disclosed |