Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796971 | 0.88 | RIPK1 (0.40) | RIPK1PLD1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5321655 | 0.86 | RIPK1 (0.40) | RIPK1PLD1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4075349 | 0.81 | HSD11B1 (0.45) | RIPK1SIGMAR1PRMT5WDR77 | |
| SCHEMBL29773951 | 0.80 | GPR119 (0.45) | RIPK1PRMT5WDR77L3MBTL1 | |
| SCHEMBL27868891 | 0.80 | GPR119 (0.45) | RIPK1PRMT5WDR77L3MBTL1 | |
| SCHEMBL1434923 | 0.80 | HTR2C (0.40) | RIPK1HTR7SIGMAR1HTR2AHTR2C | |
| SCHEMBL28938508 | 0.80 | HSD11B1 (0.40) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8496002 | 0.79 | DPP4 (0.45) | RIPK1TAAR1SIGMAR1HTR2AHTR2C | |
| SCHEMBL7668457 | 0.78 | SIGMAR1 (0.34) | RIPK1PLD1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6190053 | 0.76 | SIGMAR1 (0.43) | RIPK1PLD1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |