Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081149 | 0.92 | TLR7 (0.39) | ALOX5APSRCKDM4ETLR7ALDH1A1 | |
| SCHEMBL7080963 | 0.90 | TLR7 (0.41) | ALOX5APSRCKDM4ETLR7ALDH1A1 | |
| SCHEMBL6972848 | 0.89 | TLR7 (0.38) | ALOX5APSRCKDM4EGABRA1GABRA5 | |
| SCHEMBL6970546 | 0.89 | SRC (0.37) | ALOX5APSRCKDM4EGABRA1GABRA5 | |
| SCHEMBL7083464 | 0.88 | GRIN1 (0.39) | SRCKDM4EALDH1A1LMNA | |
| SCHEMBL6970034 | 0.88 | ALDH1A1 (0.40) | SRCKDM4EGABRA1GABRA5ALDH1A1 | |
| SCHEMBL7078348 | 0.88 | SMN1; SMN2 (0.36) | ALOX5APKDM4ETLR7ALDH1A1POLB | |
| SCHEMBL6973652 | 0.88 | SRC (0.37) | ALOX5APSRCKDM4EGABRA1GABRA5 | |
| SCHEMBL6969539 | 0.88 | GRIN1 (0.39) | ALOX5APSRCTLR7 | |
| SCHEMBL6969489 | 0.88 | ALDH1A1 (0.37) | ALOX5APSRCKDM4ETLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |