Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | HTR3A | P46098 | 3/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.59 |
| ▸ | HTR3B | O95264 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.59 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141910 | 0.87 | HTR3A (0.61) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL6927912 | 0.87 | HTR1A (0.64) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL7524534 | 0.86 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL255189 | 0.86 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL7302055 | 0.85 | LMNA (0.65) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL9319475 | 0.85 | HTR1A (0.62) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL16528267 | 0.85 | MAPT (0.69) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL787250 | 0.85 | MAPT (0.69) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Bromide SCHEMBL10621563 | 0.85 | HTR1A (0.66) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL9319232 | 0.84 | HTR1A (0.61) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | H. LUNDBECK A/S (DK) | 2003-02-27 | — | — | US | disclosed |
| EP-1246819-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. Lundbeck A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049681-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | SCLY, CBR3, TST | HTR1A 3727/4885SLC6A2 2131/4885SLC6A4 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.