Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7089666 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CYP1A1CYP1B1PKMHSD11B1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL7085847 | 0.83 | KCNH2 (0.49) | ALDH1A1ACHEKCNH2GPR3 | |
| Trifluoromethanesulfonic Acid SCHEMBL30418193 | 0.79 | ACHE (0.39) | ALDH1A1ACHEKCNH2CYP1A1CYP1B1 | |
| SCHEMBL27269877 | 0.75 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL18812855 | 0.75 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7090349 | 0.72 | GPR3 (0.41) | ALDH1A1ACHEGPR3 | |
| SCHEMBL1713657 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1PKMHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7086757 | 0.72 | GPR3 (0.38) | ALDH1A1ACHEKCNH2GPR3HSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL454992 | 0.69 | PKM (0.47) | ACHEKCNH2PKMHSD11B1 | |
| Trifluoromethanesulfonic Acid SCHEMBL1592826 | 0.69 | PKM (0.47) | ACHEKCNH2PKMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992524-B1 | Process for preparing polyether polyols | BAYER AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6624321-B2 | Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| US-20030097026-A1 | Process for the preparation of polyether polyols | DENNINGER UWE (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6492565-B2 | USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| US-20010053866-A1 | Process for the preparation of polyether polyols | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | US | disclosed |
| EP-0992524-A2 | Process for preparing polyether polyols | BAYER AG (DE) | 2000-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097026-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ALDH1A1 3594/4885ACHE 4513/4885KCNH2 1955/4885 |
| US-20010053866-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ALDH1A1 3594/4885ACHE 4513/4885KCNH2 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.