Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238584 | 0.87 | CYP1A2 (0.49) | TDP1PPARGLMNAALDH1A1CYP1A2 | |
| SCHEMBL562070 | 0.86 | KDM4E (0.49) | TDP1LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL7086877 | 0.81 | CYP1A2 (0.42) | TDP1PPARGLMNAALDH1A1CYP1A2 | |
| SCHEMBL2238587 | 0.75 | ALOX5 (0.49) | TDP1LMNAALDH1A1POLBHSD17B10 | |
| SCHEMBL561237 | 0.73 | CSNK1E (0.44) | PPARG | |
| SCHEMBL7920783 | 0.71 | KEAP1 (0.48) | TDP1LMNAHSD17B10CA12CA9 | |
| SCHEMBL562069 | 0.70 | HPGD (0.47) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL10351423 | 0.70 | TSHR (0.48) | TDP1LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL561596 | 0.70 | KEAP1 (0.47) | TDP1PPARGLMNAHSD17B10CA12 | |
| SCHEMBL10352071 | 0.70 | KMT2A (0.46) | LMNAALDH1A1KDM4EPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725107-B1 | Phosphite stabilization of polyolefins containing silica supported catalyst | GEN ELECTRIC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5514742-A | THERMOPLASTIC POLYOLEFIN RESIN WITH PHOSPHITES | GENERAL ELECTRIC COMPANY (US) | 1996-05-07 | — | — | US | disclosed |