Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561596 | 0.98 | KEAP1 (0.47) | KEAP1LMNANPC1RAB9AFFAR1 | |
| Potassium Ion SCHEMBL561597 | 0.84 | HDAC3 (0.46) | LMNANPC1RAB9AMAPK1HDAC3 | |
| SCHEMBL562070 | 0.83 | KDM4E (0.49) | LMNANPC1RAB9ATDP1KMT2A | |
| SCHEMBL2238587 | 0.80 | ALOX5 (0.49) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL2241139 | 0.80 | TDP1 (0.51) | LMNANPC1RAB9AFFAR1MAPK1 | |
| SCHEMBL10352510 | 0.79 | TDP1 (0.46) | LMNANPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL9856644 | 0.78 | NPC1 (0.43) | LMNANPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL9856413 | 0.77 | BCHE (0.60) | NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10777388 | 0.76 | ALDH1A1 (0.43) | LMNAHDAC3HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL10495848 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240462-B1 | SUBSTITUTED AMINOOXYPROPANOATE | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | claimed |
| EP-2880092-B1 | PHOSPHITE COMPOSITIONS | SI GROUP SWITZERLAND CHAA GMBH (CH) | 2020-09-30 | — | — | EP | disclosed |
| EP-2880092-A1 | PHOSPHITE COMPOSITIONS | Addivant Switzerland GmbH (CH) | 2015-06-10 | — | — | EP | disclosed |
| US-20150073073-A1 | PHOSPHITE COMPOSITIONS | ADDIVANT USA, LLC | 2015-03-12 | — | — | US | disclosed |
| US-8916065-B2 | Phosphite compositions | ADDIVANT SWITZERLAND GMBH (CH) | 2014-12-23 | — | — | US | disclosed |
| US-20140045981-A1 | PHOSPHITE COMPOSITIONS | SI GROUP, INC. | 2014-02-13 | — | — | US | disclosed |
| WO-2014020170-A1 | PHOSPHITE COMPOSITIONS | ADDIVANT SWITZERLAND GMBH (CH) | 2014-02-06 | — | — | WO | disclosed |
| US-8633267-B2 | Liquid phosphite compositions having different alkyl groups | ADDIVANT USA LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-8309635-B2 | Solid alkylaryl phosphite compositions and methods for manufacturing same | CHEMTURA CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-6224791-B1 | PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE | DOVER CHEMICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |
| EP-0635514-B1 | Neo-diol phosphites as polymer stabilizers | GEN ELECTRIC (US) | 1999-05-12 | — | — | EP | disclosed |
| US-5057563-A | Oxidation, heat, radiation stabilizers | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0240463-B1 | SUBSTITUTED AMINOOXYPROPION AMIDES | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | disclosed |
| EP-0240462-B1 | SUBSTITUTED AMINOOXYPROPANOATE | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| US-4929657-A | STABILIZERS AGAINST OXIDATION, RADIATION FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4760179-A | Substituted aminoxy-propionamides | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0240462-A2 | Substituted aminooxypropanoate | CIBA-GEIGY AG (CH) | 1987-10-07 | — | — | EP | disclosed |
| EP-0240463-A2 | Substituted aminooxypropion amides | CIBA-GEIGY AG (CH) | 1987-10-07 | — | — | EP | disclosed |